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Brian Regan () is an American stand-up comedian. Regan uses observational humor, which is also occasionally self-deprecating, and his performances are relatively "clean" as he refrains from off-color humor. Regan's material typically covers everyday events, such as shipping a package with UPS and a visit to an optometrist. Regan makes frequent references to childhood, including little league baseball, grade school spelling bees, and science projects. His clean, off-center humor has been praised by critics and contemporaries alike and Regan enjoys a fanbase that crosses young tastemakers to middle-aged adults; he is respected in the comedy community for being a "universal comic," his work has been applauded by such diverse sources as Comedy Central, Slate, The Onion and The Wall Street Journal.