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Medicine is an alternative noise-pop/rock band from the San Fernando Valley, USA. They were formed in 1991 by guitarist Brad Laner and signed to Rick Rubin's American Recordings label the following year. Medicine was/is considered the American parallel to fellow shoegazers My Bloody Valentine. With a signature guitar tone, created by running guitarist's Brad Laner's guitar through a Yamaha 4-track recorder, Medicine's music managed to distinguish itself from some of the noisier and more ambiguous endeavours of the shoegazing movement. Smashing Pumpkin Billy Corgan remixed "She Knows Everything" from Medicine's Buried Life in 1994, also adding Jimmy Chamberlin's drums to the mix.