The musical group MS MR was formed by college friends Lizzy Plaplinger and Max Hershenow while the two were students at New York's Vassar College. They graduated in 2010, the same year their first two singles, "Hurricane" and "Fantasy," were released. Besides serving as the vocalist for Ms Mr, Lizzy Plapinger is also the co-founder of the independent record label Neon Gold Records based in New York and London. Their albums have been released through IAMSOUND records and Columbia records in CD, vinyl, and digital download. Ms Mr's music has been likened to that of other alternative singers like Florence + the Machines, Chatelaine, and Lana Del Ray.
Mr Ms has appeared on the musical charts in Australia, Germany, the UK, and the US alternative list. "Hurricane" reached the number 38 spot on Germany's music charts in 2012. Their songs have been featured on the television shows Pretty Little Liars and Grey's Anatomy. The HBO series Game of Thrones used the pair's third single, "Bones" in a promotional video.